Scientist/Sr. Scientist - Cardiovascular Biology Job at Dewpoint Therapeutics, Boston, MA

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  • Dewpoint Therapeutics
  • Boston, MA

Job Description

is building a highly collaborative team to harness the power of . Together, we are leveraging a transformative shift in the understanding of cellular biology to discover and advance breakthrough therapeutics for the toughest diseases.

We are seeking a forward thinking, curious, and innovative Cardiovascular Scientist or Senior Scientist to join our pioneering team at the forefront of condensate-focused drug discovery. In this role, you will bring a deep scientific expertise in cardiovascular biology, as well as cell and molecular biology, to drive breakthrough advancements from the bench. Your experience in optimizing and validating assays for cardiovascular drug discovery will be critical in shaping our cutting-edge research efforts. Collaborating closely with cross-functional teams, you will play an integral role in advancing discovery programs that have the potential to transform patient outcomes. If you’re passionate about advancing science, thrive on overcoming challenges with integrity, and value continuous learning, we’d love to hear from you.

In this position, you’ll be part of an energizing and supportive startup team culture, engaged in continuous learning, and part of an exceptional international team. This is a lab based role located at our site in Boston's Seaport district. Dewpoint offers a flexible working environment, great benefits, competitive salary, and amazing perks.

In this role you will...

  • Provide expertise in cardiovascular biology to design, develop, and execute pharmacological assays that support our innovative drug discovery programs.
  • Independently design, optimize, and validate cell-based assays to drive meaningful progress in cardiovascular research.
  • Lead one or more scientific subject areas within the team, serving as a key contributor and thought leader.
  • Collaborate with cross-functional colleagues to ensure assays and experiments are biologically relevant, aligned with program goals, and executed effectively.
  • Mentor, inspire, and motivate team members at all levels, fostering a culture of learning and scientific excellence.
  • Enhance scientific visibility by contributing to project deliverables, presenting internally at departmental or functional meetings, and externally through conference posters, oral presentations, and peer-reviewed publications.
  • Contribute to additional initiatives and projects as they emerge in our dynamic, fast-paced environment, ensuring agility and impact.

To thrive in this role, you’ll need...

  • A Ph.D. in cardiovascular biology, cell biology, molecular biology, biochemistry, or a related scientific field.
  • A robust background in cardiovascular physiology and its applications.
  • At least 2+ years of relevant postdoctoral experience, with a proven track record of scientific achievement.
  • A strong publication record demonstrating high-impact contributions to the field.
  • Expertise in independently designing and implementing cell-based assays for drug discovery.
  • Hands-on experience with pharmacological assays for cardiomyocytes, such as calcium flux, contractility, and/or electrophysiology techniques.
  • Proficiency in working with 2D and 3D cardiac model systems.
  • Proficiency in diverse molecular biology techniques, including RT-PCR, CRISPR, siRNA, viral vectors, and transcription analysis.
  • Exceptional organizational skills with the ability to balance multiple objectives, deliver on timelines, and work independently with strong follow-through.
  • A demonstrated ability to thrive in a multidisciplinary, fast-paced, and dynamic environment while remaining solution-oriented and organized.
  • Fluent communication skills in English, enabling seamless collaboration within our vibrant and multicultural team.

Additional skills and experience that would be valuable in this role...

  • At least 2+ years of relevant industry experience in biotechnology, pharmaceuticals, and/or life sciences.
  • Proven expertise in assay analysis, including determining concentration-response data to evaluate compound potency, affinity, and dynamic response ranges of assays and biological models.
  • Experience developing in vivo pharmacological assays using animal models to support drug discovery efforts.
  • Proficiency in optimizing and validating robotic-based assays for high-throughput screening, particularly with high-content imaging technologies.
  • Strong background in in vitro assay development, execution, and high-content screening, including cellular imaging techniques.

This role offers an exciting opportunity for a solution-oriented, innovative, and curious Scientist who thrives in a collaborative, fast-paced, and forward-thinking environment. If you’re eager to delve into groundbreaking science and contribute to transformative discoveries alongside an exceptional team, we encourage you to apply!

About Dewpoint

Dewpoint Therapeutics is the first company founded to apply the emerging discipline of biomolecular condensates to drug discovery. Dewpoint believes that a vast range of conditions have pathways that are regulated by condensates or arise from the dysfunction of condensates — including cancer, neurodegeneration, and metabolic disease. Dewpoint scientists are working in Boston, MA, and Dresden and Frankfurt, Germany, to translate condensate biology into treatments for the toughest diseases.

Dewpoint strives to cultivate an inclusive international community that welcomes and empowers everyone. We reject racism, discrimination, harassment, brutality, and all other manifestations of hate. We draw strength from diversity.

Dewpoint is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status.

Please, no solicitations by agencies.

Job Tags

Flexible hours, Shift work,

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